BindingDB PrimarySearch

Found 9 hits of ec50 for drug = Advil Allergy And Congestion Relief
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Alpha-1B adrenergic receptor (Homo sapiens (Human))	BDBM50067212 (CHEBI:8093 \| Cyclomydril \| Duo-Medihaler \| Phenyle...) Show SMILES CNC[C@H](O)c1cccc(O)c1 \|r\| Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.860	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Intrinsic activity at human alpha1B adrenergic receptor expressed in CHOK1 cells co-expressing aequorin assessed as calcium mobilization measured for...				Bioorg Med Chem 24: 5582-5591 (2016) Article DOI: 10.1016/j.bmc.2016.09.017 BindingDB Entry DOI: 10.7270/Q20K2BJJ
Jagiellonian University Medical College Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Homo sapiens (Human))	BDBM50067212 (CHEBI:8093 \| Cyclomydril \| Duo-Medihaler \| Phenyle...) Show SMILES CNC[C@H](O)c1cccc(O)c1 \|r\| Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.90	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Agonist activity at alpha-1B adrenergic receptor (unknown origin) after 5 hrs by CCF4-AM staining-based cellular assay				Bioorg Med Chem 23: 2104-11 (2015) Article DOI: 10.1016/j.bmc.2015.03.009 BindingDB Entry DOI: 10.7270/Q2W37Z0Z
Jagiellonian University Medical College Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50067212 (CHEBI:8093 \| Cyclomydril \| Duo-Medihaler \| Phenyle...) Show SMILES CNC[C@H](O)c1cccc(O)c1 \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Agonist activity at alpha-1A adrenergic receptor (unknown origin) after 5 hrs by CCF4-AM staining-based cellular assay				Bioorg Med Chem 23: 2104-11 (2015) Article DOI: 10.1016/j.bmc.2015.03.009 BindingDB Entry DOI: 10.7270/Q2W37Z0Z
Jagiellonian University Medical College Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50067212 (CHEBI:8093 \| Cyclomydril \| Duo-Medihaler \| Phenyle...) Show SMILES CNC[C@H](O)c1cccc(O)c1 \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	n/a	n/a	56	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Intrinsic activity at alpha1A adrenergic receptor (unknown origin) after 5 hrs in presence of CCF4-AM by cell based beta lactamase reporter gene assa...				Bioorg Med Chem 24: 5582-5591 (2016) Article DOI: 10.1016/j.bmc.2016.09.017 BindingDB Entry DOI: 10.7270/Q20K2BJJ
Jagiellonian University Medical College Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50067212 (CHEBI:8093 \| Cyclomydril \| Duo-Medihaler \| Phenyle...) Show SMILES CNC[C@H](O)c1cccc(O)c1 \|r\| Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	155	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro agonist potency towards Alpha-1D adrenergic receptor in rat aorta				J Med Chem 39: 4116-9 (1996) Article DOI: 10.1021/jm960354u BindingDB Entry DOI: 10.7270/Q2FN18WJ
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50067212 (CHEBI:8093 \| Cyclomydril \| Duo-Medihaler \| Phenyle...) Show SMILES CNC[C@H](O)c1cccc(O)c1 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.66E+3	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro agonist potency towards Alpha-1A adrenergic receptor in rat vas deferens				J Med Chem 39: 4116-9 (1996) Article DOI: 10.1021/jm960354u BindingDB Entry DOI: 10.7270/Q2FN18WJ
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM50067212 (CHEBI:8093 \| Cyclomydril \| Duo-Medihaler \| Phenyle...) Show SMILES CNC[C@H](O)c1cccc(O)c1 \|r\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	DrugBank Article PubMed	n/a	n/a	n/a	n/a	2.95E+3	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro agonist potency towards Alpha-1A adrenergic receptor in canine prostate				J Med Chem 39: 4116-9 (1996) Article DOI: 10.1021/jm960354u BindingDB Entry DOI: 10.7270/Q2FN18WJ
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Beta-1/Beta-2/Beta-3 adrenergic receptor (Homo sapiens (Human))	BDBM50067212 (CHEBI:8093 \| Cyclomydril \| Duo-Medihaler \| Phenyle...) Show SMILES CNC[C@H](O)c1cccc(O)c1 \|r\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of H-Ras-mediated farnesylation expressed in mouse NIH3T3 cells				J Med Chem 25: 680-4 (1982) BindingDB Entry DOI: 10.7270/Q24X59ZB
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Rattus norvegicus (rat))	BDBM50067212 (CHEBI:8093 \| Cyclomydril \| Duo-Medihaler \| Phenyle...) Show SMILES CNC[C@H](O)c1cccc(O)c1 \|r\| Show InChI	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro agonist potency towards Alpha-1B adrenergic receptor in rat spleen				J Med Chem 39: 4116-9 (1996) Article DOI: 10.1021/jm960354u BindingDB Entry DOI: 10.7270/Q2FN18WJ
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair